Ellansé vs. Lafullen: Your Guide to Choosing the Right Collagen Stimulator by Treatment Area

Ellansé vs. Lafullen: Your Guide to Choosing the Right Collagen Stimulator by Treatment Area

2025-12-02Patient Resources & Tips

Hello! This is Seye Clinic, embracing all the beauty in the world, and led by a Key Doctor (KOL) and Faculty Medical Team who teach and train other medical professionals.

In recent years, there has been a significant rise in individuals seeking treatments that restore the skin's inherent elasticity for more natural results, moving beyond simple void-filling fillers.

We often meet patients concerned about how to non-surgically firm up sagging facial contours that have deteriorated with age. The new alternatives presented to these patients are Ellansé and Lafullen, both collagen stimulators based on the PCL (Polycaprolactone) component.

Today, we will explore Lafullen, which implements the novel concept of Contour Fixing, and provide a summary of its key differences from Ellansé, which has long been a market leader.

What is a Collagen Stimulator and How Does It Work?

A collagen stimulator is a substance that induces collagen generation within the dermis, improving the skin's fundamental environment. When the main component, PCL (Polycaprolactone) micro-particles, is injected, new collagen tissue is generated densely around these particles.

This mechanism is fundamentally different from Hyaluronic Acid (HA) fillers, which fill space with external material. Instead, collagen stimulators activate the skin's own regenerative capacity to improve elasticity, wrinkles, and pores while forming natural volume. Over time, the PCL particles naturally dissipate, leaving behind only the robust native collagen tissue to maintain the volume and elasticity.

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Ellansé vs. Lafullen: What is the Difference?

Both treatments use the common ingredient PCL, but they differ in core technology and key advantages. We compare them to help you choose the option best suited to your expected outcome and treatment goal.

Feature

Ellansé

Lafullen

Particle Structure

Smooth microspheres

Uniform porous microspheres

Collagen Generation Speed

Gradual generation over approx. 3-4 months

Rapid generation in just approx. 1.5-2 months

Key Advantage

Customizable longevity (1–4 years depending on the product line)

Low risk of nodule formation & high versatility

Primary Goal

Predictable and long-lasting volume

Prioritize safety, simultaneous volume and elasticity improvement

Ellansé boasts the unique advantage of Sustained Performance Technology, allowing patients to clearly select the duration of maintenance from 1 to 4 years (S, M, L, E types), which is useful for long-term aesthetic planning. Lafullen, characterized by its uniform and porous particle structure, significantly reduces the occurrence of clumping, offering a safer option for those highly concerned about side effects like nodules.

How to Choose the Right Collagen Stimulator Based on Your Concerns

The utilization of the two treatments can vary depending on the patient's concerns. For example, the choice may differ between wanting to globally refine a weakened facial contour (like with Contour Fixing) and wanting to definitively fill volume in a specific area.

Treatment Goal

Ellansé

Lafullen

Suitable Areas

Specific areas like forehead, nose bridge, cheekbones

Overall facial line correction (e.g., hollow cheeks, temples)

Concept

Volume Filler + Collagen Regeneration

Contour Fixing

Ideal Concern

Long-term, defined maintenance of specific area contours

Improvement of uneven facial lines and overall elasticity boost

Ellansé is particularly effective for specific areas requiring definitive and long-lasting volume maintenance, such as the forehead or cheeks, thanks to its Sustained Performance technology which ensures volume is 100% maintained for the specified duration.

In contrast, Lafullen, with its uniform particles, promotes even collagen generation across a broader area. It excels at gently improving facial lines through Contour Fixing, which restores the supporting structure of the face compromised by gravity and aging. Furthermore, when diluted, it can be used like a skin booster for overall skin elasticity improvement.

Essential Checks Before Undergoing a Collagen Stimulator Treatment

Since PCL-based injectables are collagen stimulators that induce your own collagen formation (often called collagen fillers), it is crucial to remember that they cannot be immediately dissolved and removed like HA fillers. This necessitates a careful and considered approach.

Why Choose Seye Clinic for this Important Treatment?

The efficacy and safety of collagen stimulators depend on 'how accurately and uniformly they are used at the desired depth.' Since the results of both Ellansé and Lafullen are highly dependent on the practitioner's skill, their expertise is more important than the product's performance alone.

Our Seye Clinic medical team consists of experts with deep knowledge and extensive clinical experience in each procedure. After a precise diagnosis of the patient's facial structure, we create a customized design based on scientific data, determining whether Ellansé's long-term volume or Lafullen's Contour Fixing will achieve the optimal improvement.


Consult with an expert to find the right treatment for you.

Ellansé and Lafullen are both excellent collagen stimulators with distinct strengths, and both choices offer natural and satisfying effects over time. We encourage you to make the most rational choice by considering your skin condition, expected results, and treatment goals.

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Seye Clinic

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Ellansé vs Lafullen: Collagen Stimulator Guide by Area