
2025-12-31 β’ Patient Resources & Tips
Hello! This is Seye Clinic, embracing all the beauty in the world, and led by a Key Doctor (KOL) and Faculty Medical Team who teach and train other medical professionals.
Lately, a specific treatment has been quietly gaining traction among dermatologists and aesthetic experts. While many boosters focus on temporary hydration, Re2O is being hailed as the "final stage of skin boosters" due to its unique ability to rebuild the skin's internal architecture.
Re2O is not your typical skin booster. It is formulated with hADM (human Acellular Dermal Matrix). A structural material derived from human tissue that has had all immunogenic cellular components removed. This leaves behind a pure scaffold of collagen, elastin, and hyaluronic acid.
As we age, our Extracellular Matrix (ECM) weakens. Re2O acts as a "biological graft," directly filling the gaps in this framework to restore density, refine pores, and provide a foundation for natural regeneration.

While Rejuran (PN) is famous for signaling cells to heal, Re2O provides the physical building blocks those cells need to work.
Category | Re2O (hADM) | Rejuran (PN) |
Core Concept | Structural Restoration | Cellular Stimulation |
Mechanism | Supplements the ECM scaffold directly | Signals fibroblasts to produce collagen |
Pain Level | Low to Moderate | High (often requires numbing) |
Downtime | Minimal (1β2 days) | Moderate (3β5 days due to bumps) |
Best For | Thin skin, large pores, structural loss | General healing, acne scars, texture |
Based on clinical observations at Seye Clinic, patients see the most significant improvement in areas where the skin has become "paper-thin" or lost its "snap." Key treatment areas include:
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Since Re2O arrives in a specialized powder form, the hydration and mixing process is critical. Improper preparation by inexperienced providers can lead to uneven results or nodules. At Seye Clinic, our faculty-led team ensures precise mixing and accurate injection depth to maximize the bio-compatibility of the hADM particles.
What is the Re2O skin booster?
Re2O is an advanced aesthetic treatment using human Acellular Dermal Matrix (hADM) to rebuild the skin's extracellular matrix (ECM). Unlike boosters that only stimulate the skin, Re2O provides a direct scaffold of collagen and elastin. It is highly effective for improving skin density, reducing fine lines, and tightening pores with less downtime and pain compared to Rejuran.
Q: How many sessions of Re2O are needed?
A: For optimal structural rebuilding, we recommend an initial phase of 2β3 sessions spaced 8β12 weeks apart.
Q: Is Re2O safe?
A: Yes. Re2O uses materials that meet strict American Association of Tissue Banks (AATB) standards, ensuring all immunogenic components are removed for high biocompatibility.
Q: When will I see results?
A: While subtle hydration is immediate, the structural firming and pore refinement typically peak around 3β4 weeks post-treatment.
Medical Disclaimer: The information is for educational purposes only and does not constitute medical advice. Please consult with a qualified dermatologist at Seye Clinic for a personalized diagnosis and treatment plan.
Seye Clinic
10F, 55 Seocho-daero 77-gil, Seocho-gu, Seoul
β’ Parking available (1h free with treatment)
Phone: +82-0507-1345-5928
Email: info@seyeclinic.com
Opening Hours: Weekdays/Evening Clinic 10:30-21:00, Weekends 10:30-19:00 (Last admission: 1 hour before closing)
Copyright Β© 2026 SEYE CLINIC. All Rights Reserved.
Seye Clinic
10F, 55 Seocho-daero 77-gil, Seocho-gu, Seoul
β’ Parking available (1h free with treatment)
Representative: Eun Sol Lee
Privacy Officer: Eun Sol Lee
Business Registration Number: 470-03-03420
Phone: +82-0507-1345-5928
Email: info@seyeclinic.com
Opening Hours: Weekdays/Evening Clinic 10:30-21:00, Weekends 10:30-19:00 (Last admission: 1 hour before closing)
Copyright Β© 2026 SEYE CLINIC. All Rights Reserved.