
2026-01-20 • Patient Resources & Tips
Hello! This is Seye Clinic, embracing all the beauty in the world, and led by a Key Doctor (KOL) and Faculty Medical Team who teach and train other medical professionals.
Are you looking to restore lost facial volume but hesitant because standard fillers disappear too quickly, while long-lasting options seem difficult to reverse? Ellanse filler, which lasts for over two years, is an attractive choice. However, because it is more complex to "melt" or correct than HA fillers, the success of the procedure depends entirely on where and by whom it is administered.
Today, we will explore the scientific basis of Ellanse—which uses your body’s natural regenerative powers—and provide an essential checklist for a successful result.
Unlike standard fillers that merely add bulk using external substances, Ellanse operates on a different mechanism. The key is PCL (Poly-caprolactone), a high-molecular-weight material approved by the FDA.

This component continuously stimulates fibroblasts within the skin, encouraging your body to produce its own new collagen and elastin. The result is not an artificial "filled" look, but a natural texture and firmness that feels like your own tissue.
Ellanse achieves both immediate satisfaction and long-term durability through a two-stage process:
Component | CMC (Gel Carrier) | PCL (Active Ingredient) |
Composition | Approx. 70% | Approx. 30% |
Primary Role | Immediate volume and shaping | Stimulates collagen & maintains for 2+ years |
Key Feature | Safely absorbed by the body over time | Creates natural, tissue-like dimensions |

Once the CMC gel provides the initial shape, the autologous collagen generated by the PCL takes its place, ensuring the promised longevity of over two years.
Ellanse maintains a firm, stable gel form, allowing it to stay exactly where it is placed. However, this high "fixation" power means it cannot be easily dissolved with enzymes if the result is unsatisfactory.

At Seye Clinic, we understand that experience equals safety—especially for irreversible procedures.

What is Ellanse filler and why does it last so long?
Ellanse is a collagen-stimulating filler composed of PCL (Poly-caprolactone) and CMC gel. Unlike HA fillers, it lasts for over 2 years by inducing autologous collagen production. It provides immediate volume via CMC and long-term structural support via PCL. Because it is difficult to dissolve, it requires a highly skilled practitioner at a specialized clinic like Seye Clinic for precise, personalized facial design.
Q: Is the procedure painful?
A: Most patients find the procedure very comfortable with just topical numbing cream. At Seye Clinic, we strictly observe numbing wait times to ensure maximum patient comfort.
Q: Which areas are best suited for Ellanse?
A: It is ideal for areas requiring structural volume and lifting, such as the forehead, temples, and mid-face (cheekbones).
Q: Are there side effects or precautions?
A: Unlike HA fillers, Ellanse cannot be easily dissolved with hyaluronidase. Therefore, verifying the practitioner's skill level and their ability to inject the correct amount in the precise layer is the most important safety precaution.
Seye Clinic
10F, 55 Seocho-daero 77-gil, Seocho-gu, Seoul
• Parking available (1h free with treatment)
Phone: +82-0507-1345-5928
Email: info@seyeclinic.com
Opening Hours: Weekdays/Evening Clinic 10:30-21:00, Weekends 10:30-19:00 (Last admission: 1 hour before closing)
Copyright © 2026 SEYE CLINIC. All Rights Reserved.
Seye Clinic
10F, 55 Seocho-daero 77-gil, Seocho-gu, Seoul
• Parking available (1h free with treatment)
Representative: Eun Sol Lee
Privacy Officer: Eun Sol Lee
Business Registration Number: 470-03-03420
Phone: +82-0507-1345-5928
Email: info@seyeclinic.com
Opening Hours: Weekdays/Evening Clinic 10:30-21:00, Weekends 10:30-19:00 (Last admission: 1 hour before closing)
Copyright © 2026 SEYE CLINIC. All Rights Reserved.