
2026-06-11 • Patient Resources & Tips
Hello! This is Seye Clinic, embracing all the beauty in the world.
When international patients visit our Gangnam clinic for pigmentation removal, the most common question is: "Which is better, PicoSure Pro or PicoPlus?" Both are advanced picosecond lasers, but they serve different purposes. PicoSure Pro excels at overall skin rejuvenation and superficial pigmentation using a 755nm wavelength, while PicoPlus utilizes multiple wavelengths (including 1064nm and 532nm) to target stubborn, multi-layered melasma and deep dermal pigmentation. Choosing the right one depends entirely on your specific skin condition.
In our practice, we consistently see patients who have tried traditional nanosecond lasers (like Q-switched Nd:YAG) with limited success or rebound pigmentation. A picosecond laser is an advanced dermatological device that delivers energy in one trillionth of a second. According to a 2022 study in the Journal of Clinical and Aesthetic Dermatology, picosecond lasers shatter melanin particles into much finer dust compared to older technologies, allowing the body's immune system to clear them away more efficiently with less thermal damage to surrounding tissue.
This ultra-short pulse duration means we can treat pigmentation, sun spots, and acne scars with fewer sessions and reduced downtime. At Seye Clinic, we perform over 200 laser toning sessions monthly, and we observe that minimizing heat is crucial for Asian skin types, which are prone to post-inflammatory hyperpigmentation (PIH).

While both devices are exceptional, they are engineered differently. Here is what we typically observe in our clinical experience:
• PicoSure Pro: Uses a single 755nm Alexandrite wavelength, which has a highly specific absorption rate for melanin. It features a specialized Platinum Focus Lens array that creates Laser-Induced Optical Breakdown (LIOB) in the epidermis. This stimulates collagen and elastin production without breaking the skin surface. It is best for overall skin brightening, improving fine lines, reducing pore size, and treating superficial freckles. However, it may not be the primary choice for very deep, dermal melasma.
• PicoPlus: A multi-wavelength platform (1064nm, 532nm, 595nm, 660nm). The versatility allows us to target pigment at various depths. The 1064nm wavelength penetrates deeper into the dermis, making it highly effective for complex, mixed-type melasma and tattoo removal. It is best for stubborn pigmentation, deep dermal melasma, post-inflammatory hyperpigmentation, and customized multi-layer treatments. A limitation is that it requires a highly skilled doctor to adjust the settings accurately to avoid over-treatment.
A question that came up three times last week alone was, "Can I just get the strongest laser?" In dermatology, stronger isn't always better; precision is key.
Feature | PicoSure Pro | PicoPlus |
|---|---|---|
Primary Target | Freckles, pores, skin texture, fine lines | Deep melasma, complex pigmentation, tattoos |
Wavelength | 755nm (Single) | 1064nm, 532nm, 595nm, 660nm (Multiple) |
Skin Rejuvenation | Excellent (via Focus Lens) | Good (via fractional handpiece) |
Downtime | 1-2 days of mild redness | Varies (1-3 days depending on intensity) |
If your goal is a "glass skin" effect—brighter tone, tighter pores, and smoother texture—PicoSure Pro is often the ideal choice. However, if you have been struggling with deep, patchy melasma for years, the deep-reaching 1064nm wavelength of PicoPlus is usually necessary.
Gangnam is the global hub for aesthetic dermatology, but technology is only as good as the doctor operating it. At Seye Clinic, we don't believe in a one-size-fits-all approach. We are led by KOL (Key Opinion Leader) doctors who deeply understand laser physics and skin anatomy.
One specific detail we emphasize is the importance of the endpoint—the clinical sign that the laser has effectively treated the pigment without causing excessive inflammation. Our doctors meticulously monitor your skin's reaction during the procedure. We also combine these lasers with premium skin boosters like Re2O or Rejuran to accelerate healing and enhance the brightening effect, a protocol highly sought after by our international patients.
👉🏻Check out the price for pico laser

When you visit Seye Clinic for a pigmentation consultation, here is what you can expect:
1. In-Depth Skin Analysis: We use advanced imaging to assess the depth and type of your pigmentation.
2. Customized Protocol: Based on the analysis, the professional consultant will recommend either PicoSure Pro, PicoPlus, or a combination of both.
3. Preparation: A topical numbing cream is applied for 20-30 minutes to ensure your comfort.
4. Precision Treatment: The doctor performs the laser treatment, constantly adjusting parameters based on real-time skin feedback. The session typically takes 15-20 minutes.
5. Soothing Care: We apply a cooling mask and regenerative LED therapy to minimize redness.
For our international patients, we provide comprehensive English aftercare instructions via WhatsApp, ensuring you know exactly how to care for your skin during your travels.
• PicoSure Pro uses a 755nm wavelength, ideal for superficial pigmentation, pore reduction, and overall skin rejuvenation.
• PicoPlus offers multiple wavelengths (like 1064nm), making it highly effective for deep, stubborn melasma and complex pigment issues.
• Picosecond technology shatters melanin into finer particles with less heat damage than traditional lasers.
• Choosing the right laser depends on a professional assessment of your pigment depth and skin goals.
• Seye Clinic in Gangnam provides customized laser protocols combined with premium skin boosters for optimal results.
Q: Which is better for me, PicoSure Pro or PicoPlus?
A: It depends entirely on your skin condition. PicoSure Pro is excellent if you want to treat superficial freckles while improving pores and skin texture. PicoPlus is better suited for deep, stubborn melasma or complex pigmentation that requires multiple wavelengths. A consultation is necessary to determine the best fit.
Q: How painful is the PicoSure Pro treatment?
A: Most patients describe the sensation as a light snapping of a rubber band against the skin. We apply a topical numbing cream for 20 to 30 minutes before the procedure, which makes the 15-minute treatment very tolerable.
Q: What is the downtime for PicoPlus?
A: Downtime varies based on the specific settings used. Typically, you may experience mild redness for 1 to 3 days. If we target specific dark spots aggressively, thin scabs may form, which naturally fall off within a week.
Q: When can I apply makeup after the laser treatment?
A: You can usually apply makeup the very next day after either PicoSure Pro or PicoPlus. However, your skin will be sensitive, so apply products gently without rubbing, and prioritize a high-quality sunscreen.
Q: Can I get laser toning if I have a tan?
A: We strongly advise against laser treatments on recently tanned skin, as the active inflammation and increased surface melanin heighten the risk of burns or hyperpigmentation. We recommend waiting until your tan has completely faded.
Ready to experience the difference? Book a free consultation via WhatsApp (+82-10-3110-9806) or browse our current events and packages. Our English-speaking team is ready to help you plan your visit.
*Disclaimer: This content is for informational purposes only and does not constitute medical advice. Individual results may vary. Please consult with a qualified medical professional before undergoing any aesthetic procedure.
Seye Clinic
10F, 55 Seocho-daero 77-gil, Seocho-gu, Seoul
• Parking available (1h free with treatment)
Phone: +82-507-1345-5928
Email: info@seyeclinic.com
Opening Hours: Weekdays/Evening Clinic 10:30-21:00 (reservation cutoff 19:00), Weekends/Public Holidays 10:30-19:00 (reservation cutoff 17:00)
Copyright © 2026 SEYE CLINIC. All Rights Reserved.
Seye Clinic
10F, 55 Seocho-daero 77-gil, Seocho-gu, Seoul
• Parking available (1h free with treatment)
Representative: Eun Sol Lee
Privacy Officer: Eun Sol Lee
Business Registration Number: 470-03-03420
Phone: +82-507-1345-5928
Email: info@seyeclinic.com
Opening Hours: Weekdays/Evening Clinic 10:30-21:00 (reservation cutoff 19:00), Weekends/Public Holidays 10:30-19:00 (reservation cutoff 17:00)
Copyright © 2026 SEYE CLINIC. All Rights Reserved.