Painless Rejuran HB Plus: Deep Hydration Without the Discomfort

Hello! This is Seye Clinic, embracing all the beauty in the world. If you want the regenerative power of Rejuran but fear the pain, Rejuran HB Plus is the answer. By combining Polynucleotides (PN) with Hyaluronic Acid (HA) and Lidocaine, this advanced skin booster reduces treatment discomfort by an average of 53% while delivering visible hydration within 14 days.

1. What is Rejuran HB Plus?

In our practice, we consistently see patients who desperately want to improve their skin's elasticity and hydration but cancel their appointments out of fear of the infamous "Rejuran pain."

Rejuran HB Plus is an advanced, hybrid skin booster designed to repair damaged skin structures while simultaneously providing deep hydration and significantly reducing injection pain. According to clinical data published by PharmaResearch (the manufacturer of Rejuran), the inclusion of a local anesthetic reduces perceived pain by 53% compared to the classic Rejuran Healer.

To put it simply, Rejuran HB Plus is a bio-revitalizing injectable that combines salmon-derived Polynucleotides (PN) for cellular regeneration, Hyaluronic Acid (HA) for intense moisture, and Lidocaine for pain relief. The classic Rejuran Healer is highly effective, but its high-density PN formula is notoriously painful to inject. For international patients visiting Seoul, the anxiety of a painful procedure can ruin their medical tourism experience. By integrating HA, which holds 1,000 times its weight in water, HB Plus not only mitigates the pain but also adds an immediate "glass skin" glow that the classic version lacks.

2. Rejuran Healer vs. Rejuran HB Plus

After performing over 5,000 skin booster treatments, one pattern we notice is that patients often struggle to choose between pure regeneration and immediate hydration. Let's compare the two objectively:

• Classic Rejuran Healer: Contains pure, high-concentration PN. It is the gold standard for deep tissue repair, acne scar healing, and collagen synthesis. However, it lacks hydrating properties and has a high pain level (often rated 8/10 by patients).

• Rejuran HB Plus: Contains a synergistic blend of PN and HA, plus Lidocaine. It offers dual benefits: structural repair and immediate moisture. The pain level is significantly lower (typically rated 3/10 or 4/10).

We believe in being completely honest about limitations. Because HB Plus shares its volume with HA and Lidocaine, the absolute concentration of PN per cc is slightly lower than the classic Healer. Therefore, if your only goal is treating severe atrophic acne scars, the classic Healer might require fewer sessions. However, for overall anti-aging, hydration, and fine line reduction, HB Plus provides a much more comfortable and well-rounded result. Typically, we recommend a baseline of 3 sessions spaced 3 to 4 weeks apart for optimal longevity, which usually lasts 6 to 9 months.

3. What to Expect: Pain, Downtime, and Cost

A question that came up three times last week alone from our international patients was: "Will I be able to go shopping in Gangnam right after the treatment?"

In our clinical experience, the downtime for Rejuran HB Plus is highly manageable. Here is a quick breakdown of what to expect:

What we typically observe is that the "embossing" effect—small, mosquito-bite-like bumps on the skin—subsides much faster with HB Plus than with the classic Healer. Because the HA makes the solution slightly less viscous, the bumps usually flatten within 24 hours. The cost is slightly higher per cc than standard skin boosters, but the 53% reduction in pain and the added hydration make it a premium choice that over 90% of our returning patients prefer.

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4. Why Choose Seye Clinic in Gangnam, Seoul?

Seoul is the global capital of aesthetic dermatology, but not all clinics approach skin boosters the same way. At Seye Clinic, located just 1 minute from Gangnam Station, we treat Rejuran HB Plus not as a one-off procedure, but as a core component of a long-term "comfortable skin management" strategy.

As a certified Re2O Key Clinic and a leading facility for advanced injectables, our doctors possess a profound understanding of dermal layers. One specific detail that only a practitioner at Seye Clinic would know is the exact angle and depth required for the HB Plus injection. Because it contains HA, injecting it too superficially can cause prolonged bumps, while injecting it too deeply wastes the PN in the subcutaneous fat. We use a specialized micro-injection technique, adjusting the needle depth to exactly 1.0mm to 1.5mm depending on the patient's epidermal thickness, ensuring zero product leakage and maximum absorption.

5. Seye Clinic's Approach to Your Treatment

When you visit Seye Clinic in Gangnam, your experience is tailored from start to finish.

First, we conduct an in-depth consultation using advanced skin analysis to determine if Rejuran HB Plus is the right fit, or if a rotation with other boosters like CEllRDM or Juvelook would yield better results. Even though HB Plus contains Lidocaine, we apply a premium topical anesthetic for 20 to 30 minutes to ensure absolute comfort.

Our KOL (Key Opinion Leader) specialist doctors then perform the procedure using meticulous hand-injection techniques. Afterward, we provide specialized soothing treatments to accelerate the reduction of embossing. For our international patients, our English-speaking team ensures seamless communication, and we offer tax-free services and convenient parking (1 hour free) right in the heart of Seocho-gu.

Quick Summary

• Dual Action: Combines PN for regeneration and HA for deep hydration.

• Painless: Built-in Lidocaine reduces injection pain by an average of 53%.

• Fast Recovery: Embossing typically subsides within 24 to 48 hours.

• Expert Delivery: Seye Clinic's precise hand-injection technique prevents product leakage.

Frequently Asked Questions

Q: Should I choose Rejuran Healer or Rejuran HB Plus?

A: If your primary goal is treating severe acne scars, the classic Healer's pure PN is ideal. However, if you want overall anti-aging, deep hydration, and a comfortable experience with 53% less pain, Rejuran HB Plus is the superior choice.

Q: Is Rejuran HB Plus really painless?

A: While no injection is 100% painless, Rejuran HB Plus contains Lidocaine, which clinical studies show reduces pain by 53% compared to the classic version. Combined with our premium topical numbing cream, most patients find it highly tolerable.

Q: How long does it take to see results from Rejuran HB Plus?

A: You will notice an immediate boost in hydration and a "glass skin" glow within 3 to 5 days due to the Hyaluronic Acid. The structural regeneration and collagen production from the PN typically become visible after 2 to 4 weeks.

Q: How long do the bumps (embossing) last after the procedure?

A: The small bumps, known as embossing, usually subside within 24 to 48 hours. Because the HB Plus formula is slightly less viscous than the classic Healer, the fluid disperses into the dermal layers much faster.

Ready to experience the difference? Book a free consultation via WhatsApp (+82-10-3110-9806) or browse our current events and packages. Our English-speaking team is ready to help you plan your visit.

*Disclaimer: This content is for informational purposes only and does not constitute medical advice. Individual results may vary. Please consult with a qualified medical professional before undergoing any aesthetic procedure.