
2025-12-09 • Patient Resources & Tips
Hello! This is Seye Clinic, embracing all the beauty in the world, and led by a Key Doctor (KOL) and Faculty Medical Team who teach and train other medical professionals.
Many patients visit us interested in skin rejuvenation but hesitant because of the "notorious" pain associated with Rejuran reviews. If you have been delaying your treatment due to the fear of needles or discomfort, you will be happy to hear that a "Pain-Free Rejuran" option exists. Today, we will compare the classic Rejuran Healer with the newer Rejuran HB Plus.
Rejuran is a premium skin booster that injects Polynucleotides (PN), extracted from salmon DNA, directly into the dermal layer.

The level of discomfort depends on which version of Rejuran you choose. The difference lies in the formulation of Rejuran Healer versus Rejuran HB Plus.
Feature | Rejuran Healer | Rejuran HB Plus (Pain-Free) |
Key Ingredients | Polynucleotide (PN) | PN + Hyaluronic Acid (HA) + Lidocaine |
Pain Level | Relatively High | Significantly Reduced |
Focus | Intense Regeneration | Regeneration + Hydration + Comfort |
Rejuran HB Plus earned its "Pain-Free" nickname because it contains Lidocaine (a local anesthetic) and Hyaluronic Acid (HA). This combination reduces pain by approximately 50% while adding an extra boost of hydration.
Your choice should depend on your pain tolerance and specific skin goals.
Beyond the product itself, the injection technique is vital for a painless result. At Seye Clinic, we go the extra mile to ensure your comfort:
Whether you choose the classic or the pain-free version, proper aftercare ensures the best results:
If pain has been your only barrier to healthier skin, Rejuran HB Plus is the perfect alternative. The most important step is finding the right solution through a professional diagnosis.
Seye Clinic
10F, 55 Seocho-daero 77-gil, Seocho-gu, Seoul
• Parking available (1h free with treatment)
Phone: +82-0507-1345-5928
Email: info@seyeclinic.com
Opening Hours: Weekdays/Evening Clinic 10:30-21:00, Weekends 10:30-19:00 (Last admission: 1 hour before closing)
Copyright © 2025 SEYE CLINIC. All Rights Reserved.
Seye Clinic
10F, 55 Seocho-daero 77-gil, Seocho-gu, Seoul
• Parking available (1h free with treatment)
Representative: Eun Sol Lee
Privacy Officer: Eun Sol Lee
Business Registration Number: 470-03-03420
Phone: +82-0507-1345-5928
Email: info@seyeclinic.com
Opening Hours: Weekdays/Evening Clinic 10:30-21:00, Weekends 10:30-19:00 (Last admission: 1 hour before closing)
Copyright © 2025 SEYE CLINIC. All Rights Reserved.